Tumor Angiogenesis 2012
نویسندگان
چکیده
منابع مشابه
Tumor Angiogenesis 2012
It has been more than 40 years since the initial prospect emerged that tumor angiogenesis could be targeted for cancer therapy. This proposal was based on the very simple observation that tumors are capable of stimulating new vascularization. Later the concept of an angiogenic switch was proposed; where cancer cells evolve from a dormant state into angiogenic phenotype attracting blood vessels ...
متن کاملangiogenesis and tumor
angiogenesis, the process of new blood vessel formation from existing ones, plays an important role in the physiologic circumstances such as embryonic development, placenta formation, and wound healing. it is also crucial to progress of pathogenic processes of a variety of disorders, including tumor growth and metastasis. in general, angiogenesis process is a multi-factorial and highly structu...
متن کاملTumor Angiogenesis
The hypothesis that tumors are angiogenesis dependent has, in the past decade, generated new investigations designed to elucidate the mechanism of angiogenesis itself. Many laboratories are now engaged in this pursuit. Some are studying angiogenesis that occurs in physiological situations, whereas others are interested in angiogenesis that dominates pathological conditions. These efforts have l...
متن کاملTumor Angiogenesis
In a seminal New England Journal of Medicine article, published 40 years ago, Folkman proposed the concept that angiogenesis could be a target for cancer therapy [1]. This proposal emerged from early observations that some tumors cells were capable of stimulating endothelial cells to form new capillary sprouts and that nonvascularized tumors were held in a dormant state, unable to grow beyond a...
متن کاملPlants as useful agents for angiogenesis and tumor growth prevention
Introduction: Angiogenesis, the process of new blood vessel formation from pre-existing vessels, has important physiological roles in embryonic development, female reproduction cycle, and wound healing. It is also crucial for pathological processes in several diseases especially tumor growth and metastasis. Thereby, inhibition of angiogenesis as an addition to the conventional therapies such...
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ژورنال
عنوان ژورنال: Journal of Oncology
سال: 2012
ISSN: 1687-8450,1687-8469
DOI: 10.1155/2012/857383